The Effect of Exercise Intensity on Aging

September 9, 2021 by
Photo Credit: Training Day Media (instagram.com/trainingdaymedia)

I love the human genome project. It was a 13 year-long publicly funded international scientific research project that set out to identify and map all the genes, down to the specific DNA base pairs, of the human genome. It has done more to advance our understanding of molecular medicine and human evolution than any other scientific endeavor. Ever. It has helped us understand cancer and genotype viruses. It has advanced forensic science and individualized biotherapeutics. When the cures for cancers are discovered, we will certainly have the human genome project to thank for that.

Scientists are now able to evaluate DNA and site-specific differences between individuals to understand the impact that our environment and behaviors have on gene activity and expression. 

Epigenetics is the study of these changes. Epigenetics refers to the heritable alterations that are not due to changes in DNA sequence (like single nucleotide polymorphisms) but rather “tags” such as DNA methylation and histidine modification. These alter DNA accessibility and chromatin structure which impact our gene expression (what we do with our DNA). 

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